Liverpool John Moores University has appointed CBRE to find a new owner for the 20-acre former IM Marsh campus in Aigburth.
Offers are sought by the end of May on either an unconditional or subject-to-planning basis.
The development site is situated off Barkhill Road in the southern part of the city and contains a range of buildings, including two with Grade II listed status, totalling 213,000 sq ft.