Canary Wharf Group has got the green light for a 700,000 sq ft office building at 1 Bank Street, E14.
The Kohn Pederson Fox-designed scheme will rise to 27 storeys with retail space at the ground floor.
Banking giant Société Générale has already agreed a lease for 280,000 sq ft at the development.
It will occupy the ground and first to seventh floors on a 25-year lease at a rent of £47.50 per sq ft.
Sir George Iacobescu, chairman and chief executive of Canary Wharf Group, said: “Today’s decision highlights Canary Wharf’s position as one of the most attractive places to work.”
The developer, which is expected to be integrated with majority owner Songbird Estates as part of a takeover by Qatar Investment Authority and Brookfield, secured the consent from Tower Hamlets council.